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Welcome to the Psychopharmacology of Memory Modulation Lab.

Principal Investigator: Patrizia Campolongo

Our laboratory is located at the Department of Physiology and Pharmacology “V. Erspamer” of Sapienza University of Rome.

Our research focuses on the effects of stress on memory function, investigating the role of different neural circuits that mediate behaviour in response to stress. Particularly, our laboratory investigates the role of the endocannabinoid system in regulating memory consolidation, memory retrieval and memory extinction and its specific action in response to both acute and chronic stressors. Our research aims at providing important insights on the brain mechanisms that are affected by stress in physiological and pathological conditions and may improve our ability to identify therapeutic targets for stress-related disorders.

Our research interests have recently expanded from rodents to human settings to explore the neural mechanisms underlying the development of cognitive disorders in PTSD patients and neurobiological underpinnings of memory processes in a unique Italian human population of subjects with highly superior autobiographic memory (HSAM).